Top-Rated Brain Supporting Supplements

Which Have Made To The Top This Year?

68 Nootropic Supplements

3 Experts Consulted

10 Top Picks

Today, one of the most sought-after supplement categories revolves around enhancing brain and memory functions. Referred to as nootropics, these supplements aim to bolster memory, concentration, mental vitality, and problem-solving abilities.

The demand for nootropics isn’t solely driven by the 73 million baby boomers residing in America but also extends to college students, investment bankers, career-driven individuals, and even busy moms, all striving for a competitive edge.

However, this surge in popularity has inundated the market with numerous nootropic supplements. Despite their promising claims, many of these products fail to deliver. Some prominent brands utilize ineffective or inadequate ingredient doses, while others incorporate low-grade fillers.

Given the abundance of options, it’s understandable if consumers feel uncertain about selecting a quality brain and memory supplement. To streamline the decision-making process, we’ve conducted extensive research to identify key ingredients proven to enhance cognitive health.

This concise guide aims to equip you with the knowledge necessary to discern quality supplements from subpar ones, enabling you to make informed choices regarding your nootropic needs. Additionally, we’ll highlight the top 10 nootropic supplements available today.

Before delving into specific products, let’s take a moment to explore how nootropics function to enhance cognitive health and why integrating them into your daily regimen is crucial.

What to Avoid When Buying a Cognitive Supplement

Here’s an important quick guide when looking at a brain enhancement product and trying to decide if it’s the right one for you:

  1. NO: If its formula lacks essential vitamins and nutrients
    Your brain gobbles up an ongoing supply of vitamins, minerals, and nutrients for its proper – and outstanding – functioning. Avoid products that don’t offer these important components. 
  2. YES: Backed by clinical data and experts
    Effective nootropic support requires a solid scientific basis by way of independent, third-party research data on product effects and benefits. A great formula is supported by a credible health care expert who has the background and experience in brain enhancement. 
  3. NO: Insufficient return policy and fraud
    Reputable nootropic companies offer 100% money-back guarantee on their supplement if they are confident enough that it works. They also won’t fool around with a limited and deceitful return policy, as well as auto-shipping that you aren’t even aware of! Make it a habit to read the fine print for your protection. 
  4. YES: Independent reviews (Not just Amazon!)
    The internet is filled with unverified as well as bought reviews, so vigilance is key. Develop an eye for truly impartial reviews that have your best interest at heart, not content masquerading as independent reviews in order to get you to buy a specific brand. This is why we have our own circle of product testers to separate facts from myths and really present the best performers in the market. 

A key here is your due diligence in product research and review, so that you have accurate and up-to-date information helping you choose a the right supplement for you. 

Natural nootropics consist of a blend of vitamins, amino acids, minerals, fatty acids, antioxidants, and various herbal ingredients, either natural or synthetic. These components are combined in supplements with the aim of enhancing cognitive performance.

A High-Quality Nootropic Aids in:

Improving Memory, Enhancing Focus and Alertness, Promoting Learning, Supporting Verbal Recall, Boosting Analytical Thinking, Increasing Mental Energy, Fostering Creativity, Reducing Stress, Slowdown Cognitive Decline.

A decade-long study involving over 7,000 adults aged 45-70 has highlighted that cognitive decline commences as early as 45 years of age. Alarmingly, participants in the 65-70 age bracket exhibited a 300% increase in cognitive decline compared to those aged 45-49. This underscores the acceleration of brain degeneration with age, leading to more noticeable declines.

Further investigations have revealed that individuals experiencing cognitive impairment often display deficiencies in essential vitamins and nutrients crucial for protecting against cognitive decline. Researchers have identified specific nutrients essential for cellular activity, vital for sustaining optimal cognitive function.

Additionally, chronic stress has been linked to hastened cognitive decline and impaired memory function. Certain nootropics incorporate ingredients classified as adaptogens, aiding the body in managing stress and consequently enhancing cognitive performance.

Top 4 Criteria For A Quality Nootropic Supplement

We spent months researching nootropic supplements and gathering user feedback. There are specific ingredients that, when present in a formula, help differentiate high-quality nootropic supplements from generic ones. Below are the three most essential ingredients to consider before deciding on which nootropic brand is best for your needs.

#1 Alpha GPC (alpha-lycerophosphocholine)

Alpha-GPC is a natural compound found in the brain and various food sources. It serves as a choline donor, contributing to the production of the neurotransmitter acetylcholine, which plays a crucial role in cognitive function, memory, and muscle control. Alpha-GPC is often used as a dietary supplement to support cognitive health, enhance memory, improve learning, and promote athletic performance. It’s valued for its high bioavailability and ability to readily cross the blood-brain barrier, making it an effective option for supporting brain health and cognitive function.

#2 Phosphatidylserine

Phosphatidylserine (PS) is a phospholipid compound found in high concentrations in the brain. It plays a vital role in various brain functions, including cell membrane structure, signal transduction, neurotransmitter release, and synaptic activity. Phosphatidylserine is known for its potential cognitive benefits, such as improving memory, attention, and cognitive performance, particularly in older adults. It’s also involved in stress response and may help mitigate the negative effects of cortisol, a stress hormone, on the brain. Phosphatidylserine supplements are commonly used to support brain health, particularly in individuals experiencing age-related cognitive decline or memory problems.

#3 Ginkgo biloba

Ginkgo biloba is a tree native to China, revered for its brain-enhancing properties. Derived from its leaves, ginkgo biloba extract is a popular supplement known for improving memory, concentration, and cognitive function. It’s believed to enhance blood flow to the brain, promoting mental clarity and reducing age-related cognitive decline. 

#4 Noopept

Noopept is a synthetic nootropic compound known for enhancing cognitive function and brain health. It improves memory, learning, and cognitive performance while also providing neuroprotection against oxidative stress. Additionally, it may boost mood and promote brain plasticity. May Increase brain plasticity as it may support the growth of new neural connections and promote brain plasticity, which is important for learning and adaptability.

Top 10 Brain Enhancing Pills



Overall Rating: 9.7/10
Ingredient Quality: 9.8/10
Brain Enhancing Power: 9.6/10
Long Term Results: 9.7/10
Custom Reviews: 9.6/10
Safety: 9.8/10
Side Effects: None
Guarantee: 90 Days
Servings: 30 Days

Retail Price:
$36.33 – $57.97
The real-life Limitless Pill? One of the newer offerings in the nootropic industry, Avanse Laboratories’ new ingenious formula LumULtra has been generating quite much popularity on the internet, and has been buzzing around on dedicated nootropic forums. Why do we pick this awesome formula to be the #1 nootropic supplement of 2022 and 2023? Simple, name another supplement that contains “potent 1160mg capsule” and has just recently been upgraded to 25 mg of world's most powerful nootropic agent Noopept. It is cheap, in our opinion, compared to what it contains. And we don’t think their price will stay this low for long. Avanse Laboratories is currently playing… Learn More...


Overall Rating: 9.2/10
Ingredient Quality: 9.1/10
Brain Enhancing Power: 9.2/10
Long Term Results: 9.0/10
Custom Reviews: 9.1/10
Safety: 9.0/10
Side Effects: None
Guarantee: 60 Days
Servings: 30 Days

Retail Price:
There is much to be appreciated in a brain supplement like BrainPill (never mind the confusion that may stem from the generic-sounding name) that combines tried-and-tested ingredients in a single one-a-day formulation. The consistency in claims and what users see in real life is an exemplary one, which convinces us to rate this powerhouse as the second on this review list. Feeding one’s brain with nootropics and related supplements entails due diligence in research and seeking the highest quality, and we think BrainPill is up to task. Learn More...


Overall Rating: 9.0/10
Ingredient Quality: 8.9/10
Brain Enhancing Power: 8.9/10
Long Term Results: 8.8/10
Custom Reviews: 9.0/10
Safety: 8.9/10
Side Effects: none
Guarantee: 30 Days
Servings: 30 Days

Retail Price:
Neuriva is definitely backed by a big-name supplement maker. It has attracted enough attention to be stocked by big retailers and enjoy a solid following. First-time nootropic users, however, have to be very discriminating in their first brain pill of choice, as it will set the tone for their ongoing use and supplementation. There’s a scarcity in important product information here, including clinical findings, comparison with peers, and transparent details that will show us it’s an inevitable part of one’s brain-boosting regimen. Learn More...

Alpha Brain

Overall Rating: 8.9/10
Ingredient Quality: 8.8/10
Brain Enhancing Power: 8.6/10
Long Term Results: 8.7/10
Custom Reviews: 8.7/10
Safety: 8.8/10
Side Effects: none
Guarantee: 90 Days
Servings: 15 Days

Retail Price:
It’s refreshing to have a nootropic like Alpha Brain that doesn’t put the entire industry to shame. By this we mean it’s relatively safe for intake and the makers are pretty transparent and upfront about their blend and its ingredients. Now, onto the downside, we aren’t as confident taking Alpha Brain as we do with other newcomers in the market, for the simple reason that the documented side effects are numerous. We can “ignore” a few reactions, but with so much variation in every person’s brain chemistry and reaction to supplements, it should be quite alarming to get so many complaints of side effects from different people. Learn More...


Overall Rating: 8.7/10
Ingredient Quality: 8.6/10
Brain Enhancing Power: 8.5/10
Long Term Results: 8.5/10
Custom Reviews: 8.6/10
Safety: 8.5/10
Side Effects: none
Guarantee: 45 Days
Servings: 30 Days

Retail Price:
Their main claim is Memory Improvement. They also suggest Prevagen supports Healthy Brain Function, Sharper Mind, and Clearer Thinking. Their website states they were voted “#1 Brain Health Support Supplement”. The manufacturer is Quincy Bioscience. Prevagen comprises just a single ingredient – Apoaequorin” – which they claim was originally found in certain species of jellyfish. Prevagen was clinically tested and showed an increase in memory in healthy adults over 40 years old. Prevagen comes in 3 varieties with Chewables, Original and Extra Strength. Learn More...


Overall Rating: 8.5/10
Ingredient Quality: 8.5/10
Brain Enhancing Power: 8.4/10
Long Term Results: 8.4/10
Custom Reviews: 8.5/10
Safety: 8.5/10
Side Effects: none
Guarantee: Moneyback
Servings: 30 Days

Retail Price:
Overall impressions of the product is that it may work a little, but it does not deliver on all of its promises. Participants only noticed an improvement in their concentration, but not in their memory. Some participants didn't experience any changes at all. Memotenz also says that there should be no side effects, but based on our participants, this is not true. Side effects may include sleepiness, dizziness, headaches, or insomnia. Learn More...


Overall Rating: 8.1/10
Ingredient Quality: 8.2/10
Brain Enhancing Power: 8.1/10
Long Term Results: 8.1/10
Custom Reviews: 8.2/10
Safety: 8.1/10
Side Effects: none
Guarantee: 90 Days
Servings: 30 Days

Retail Price:
People who have tried Neuronol report the same thing as our participants. The positive effects of boosted energy and better focus are almost immediate, but fade over the course of taking this supplement. People didn't really report any long-term effects, despite Neuronol's claim to help boost long-term memory. Some people said that taking Neuronol does help with clarity, or reducing "brain fog," but that this also fades over time. The short-term effects of Neuronol are likely because of the caffeine and taurine acting as stimulants, rather than any real brain-boosting effects from the other ingredients. Learn More...

Optimind Pro

Overall Rating: 7.8/10
Ingredient Quality: 7.8/10
Brain Enhancing Power: 7.8/10
Long Term Results: 7.7/10
Custom Reviews: 7.8/10
Safety: 7.8/10
Side Effects: none
Guarantee: 60 Days
Servings: 30 Days

Retail Price:
Optimind Pro is backed by an established company, enjoys warm reception in the market if reviews and testimonials are to be believed, and may be getting the job done. But it is not unchallenged in such a strongly competitive industry, with other players offering more optimum brain nourishment at a more cost-effective price and greater safety value. These gems can be found at the top of this list. Optimind is one worth considering, however, particularly among beginners in nootropics and those looking for a safe, conservative choice. Learn More...

Neuro Peak

Overall Rating: 7.5/10
Ingredient Quality: 7.4/10
Brain Enhancing Power: 7.4/10
Long Term Results: 7.4/10
Custom Reviews: 7.5/10
Safety: 7.5/10
Side Effects: none
Guarantee: 60 Days
Servings: 30 Days

Retail Price:
It’s easy to appreciate and consider a nootropic like Neuro-Peak because of its sheer simplicity in ingredient list, once-daily dose, and even benefit claims. It’s uncomplicated and unproblematic in what it strives to do. It also enjoys significant numbers of customer reviews, which could signal trustworthiness at current rating levels. The only letdown, however, is that the product literature doesn’t say much of potential side effects or any safety reminders. Safety is a crucial aspect and one that is never to be ignored or forgotten. Learn More...

Mind Lab Pro

Overall Rating: 5.5/10
Ingredient Quality: 5.1/10
Brain Enhancing Power: 5.3/10
Long Term Results: 5.5/10
Custom Reviews: 5.2/10
Safety: 5.5/10
Side Effects: none
Guarantee: 30 Days
Servings: 30 Days

Retail Price:
Mind Lab Pro can very well be considered one of the giants of nootropics today. It’s popular in online sites, it has thriving social media promotions, and we find that it’s well-stocked online and in brick and mortar stores, too. Learn More...